The table below shows drug alerts, medicines recalls and company-led drug alerts issued in England, Northern Ireland, Scotland and Wales. The information in this table will be updated on an ongoing basis.

Date published

Alert

Countries

18/9/2020 MHRA alert – Important changes to MHRA alerts and amendments to CAS website UK
16/9/2020 Class 2 FMD Medicines Recall: multiple parallel distributed medicines
UK
10/9/2020 CMO messaging: withdrawal of PPE guidance published 17 April 2020 England
10/9/2020 Class 4 Medicines Defect information: Zopiclone tablets UK
7/9/2020 Class 3 Medicines Recall: Amlodipine 10mg Tablets UK
3/9/2020 Medicine supply notice: Lithium carbonate (Priadel®) 200mg and 400mg modified release tablets  Scotland
1/9/2020 Class 4 FMD Medicines Information: Kingsley Specials Ltd UK
1/9/2020 Class 2 Medicines Recall: Oxylan prolonged-release tablets 40mg UK
27/8/2020 Medicine supply alert notice: Esomeprazole 40mg iv powder for solution Scotland
27/8/2020 Medicine supply alert notice: Normacol and Normacol Plus England and Scotland
26/8/2020 Medicine supply alert notice: H2-antagonists (cimetidine, famotidine and nizatidine) Scotland
26/8/2020 Medicine supply alert notice: Oral Contraceptive tablets (various brands) Scotland
26/8/2020 Medicine supply alert notice: Diazepam (Diazemuls®) emulsion for injection 10mg/2ml Scotland
26/8/2020 Medicine supply alert notice: Prednisolone suppositories 5mg Scotland
26/8/2020 Medicine supply alert notice: Nabumetone tablets 500mg Scotland
26/8/2020 Medicine supply alert notice: Lodoxamide eye drops 01% Scotland
25/8/2020 Drug alert: Update: Amoxicillin Sodium Powder for Solution for Injection 1g, 250mg and 500mg (Wockhardt UK Ltd) UK
24/8/2020 Class 2 drug alert Action within 48 hours: Fasturtec powder and solvent for concentrate for solution for infusion 7.5mg/5ml (Sanofi) England
21/8/2020 Supply disruption alert: Priadel® modified-release tablets 200mg and 400mg England
18/8/2020 CMO Messaging: COVID-19 Research and treatment trials England
14/8/2020 PPE dedicated supply channel important customer alert: Flosteril FLO-MED-8130 non-sterile gowns England
13/8/2020 Drug Alert: SmofKabiven extra Nitrogen Electrolyte Free UK
13/8/2020 NPSA alert: Steroid Emergency Card to support early recognition and treatment of adrenal crisis in adults England
11/8/2020 Medicine supply alert notice: Pethidine 50mg tablets Scotland
11/8/2020 Medicine supply alert notice: Sulfasalazine 250mg-5ml oral suspension (Rosemont) Scotland
10/8/2020 Drug alert: Phosphates Solution for Infusion 500ml (Huddersfield Pharmacy Specials MS 19055) UK
6/8/2020 NPSA alert: Risk of death from unintended administration of sodium nitrite England
5/8/2020 Medicine supply alert notice: Tuberculosis (TB) oral agents Scotland
5/8/2020 Medicine supply alert notice: Senna with ispaghula husk (Manevac®) granules (Mylan) Scotland
5/8/2020 Medicine supply alert notice: Nabumetone 500mg Tablets Scotland
5/8/2020 Medicine supply alert notice: H2-antagonists (cimetidine, famotidine and nizatidine) Scotland
4/8/2020 Drug alert: Clexane 4,000 IU (40mg) /0.4ml Syringes (Pharmaram Ltd) Scotland
4/8/2020 Drug alert: Clexane 4,000 IU (40mg)/0.4ml Syringes (Pharmaram Ltd) England, Northern Ireland and Wales
3/8/2020

Medicines defect information: SyreniRing vaginal delivery system 0.120mg/0.015mg per 24 hours (Crescent Pharma Ltd)

UK
3/8/2020

Drug recall: Digoxin tablets 250mcg (Accord-UK Ltd)

UK
29/7/2020

Drug recall: Abstral sublingual tablets 200mcg (Kyowa Kirin Limited)

UK
24/7/2020

Evidence of harm from illicit or fake benzodiazepines

England
23/7/020

Drug Recall:  Irinotecan hydrochloride concentrate for solution for infusion 20mg/ml (5ml vial)

England, Northern Ireland and Scotland
23/7/2020 Drug Alert: information Ecalta 100mg powder for concentrate for solution for infusion England, Northern Ireland and Scotland
21/7/2020 DHSC alert: cannabis oil has been found disguised as confectionary England
20/7/2020

Drug alert: Trimogal tablets 100mg (Ennogen Pharma)

England and Scotland
20/7/2020

Medical device alert: Cardinal Health type IIR facemasks alert

England
20/7/2020

Drug alert: Ibuprofen 200mg and 400mg tablets packaged in various liveries (Aspar Pharmaceuticals Limited)

Scotland
20/7/2020

Drug alert: Ibuprofen 200mg and 400mg tablets packaged in various liveries (Aspar Pharmaceuticals Limited)

Northern Ireland 
20/7/2020

Drug alert: Ibuprofen 200mg and 400mg tablets packaged in various liveries (Aspar Pharmaceuticals Limited)

England and Wales
15/7/2020

Drug Alert: Nitrofurantoin tablets 50mg, Dr Reddy’s Laboratories (UK) Ltd (15/07/2020)

England, Northern Ireland and Wales
15/7/2020

Drug Alert: Desmopressin nasal spray (all strengths) Ferring Pharmaceuticals Limited

England, Scotland and Wales
15/7/2020

Drug alert: Desmospray® 0.1 mg/ml Nasal Spray 

Northern Ireland
8/7/2020

MSN: Pregaday® (ferrous fumarate 322mg/folic acid 350mcg) tablets (08/07/20)

England, Northern Ireland and Scotland
8/7/2020

MSN: Intal® (sodium cromoglicate) CFC-free inhaler 5mg/dose (08/07/20)

England and Northern Ireland
1/7/2020 MSN: Mitomycin 2mg England
01/7/2020 Drug Recall: Mepacrine hydrochloride tablets 100mg UK
30/6/2020 Drug Alert: Depo-Provera injection 150mg/ml England, Scotland, Northern Ireland
30/6/2020 Medicine supply alert: Fluticasone propionate (Flixotide®) 0.5mg/2ml and 2mg/2ml Nebules Scotland
30/6/2020 Medical drug alert: Philips HeartStart XL Defibrillator/Monitor England
29/6/2020

Drug safety alert: Reducing the risk of meningioma with cyproterone acetate

UK
29/6/2020

Drug safety alert: Direct-acting oral anticoagulants (DOACs) — increased bleeding risk

UK
29/6/2020 Medicine supply alert: Prednisolone 5mg Suppositories (RPH Pharmaceuticals) Scotland
29/6/2020 Medicine supply alert: Promazine 25mg and 50mg tablets Scotland
29/6/2020 Medicine supply alert: Phenytoin sodium NRIM 100mg capsules Scotland
26/6/2020

Customer alert: Cardinal Health Type IIR masks alert

UK
26/6/2020

MHRA approves recruitment of further participants into hydroxychloroquine clinical trial

UK
25/6/2020 MSN: Flixotide nebules England
25/06/20 SDA: Nardil® (Phenelzine sulphate) tablets 15mg (25/06/20) England, Northern Ireland, Wales
25/06/20 MSN: Mirtazapine orodispersible tablets 15mg and 45mg UK
25/6/2020 MSN: Alomide® (lodoxamide) eye drops 0.1% England, Northern Ireland, Scotland
25/6/2020 MSN: Imipramine tablets 25mg UK
25/6/2020 MSN: Vimpat® (lacosamide) tablets 50mg England
23/6/2020 CAS alert: risk of heat stress whilst wearing PPE in warn/hot weather England
19/6/2020 Medicine supply alert: H2-antagonists (cimetidine, famotidine and nizatidine) Scotland
18/6/2020 MSN TB oral agents Update 7 England
17/6/2020 Medical device alert: Philips HeartStart MRx Monitor/Defibrillators England
16/6/2020 MSN: levodopa +carbidopa+ entacapone tablets- various strengths and brands England
16/6/2020 CAS alert: Dexamethasone approved to treat hospitalised COVID-19 patients UK
12/6/2020 MSN: Ranitidine- all formulations (clinical update) England
12/6/2020 MSN: oxaliplatin Update England
10/6/2020 MSN: Prednisolone 5mg Suppositories England
9/6/2020 Second update – Early Access to Medicines Scheme for Remdesivir in the treatment of COVID-19. Implementation of the scheme and management of supply UK
8/6/2020 MSN: Solu-Medrone 1g England
8/6/2020 MHRA medical device alert (8/6/20) ISSUED: Results from laboratory-based tests for COVID-19 antibodies using capillary blood sample collection kits may not be reliable (MDA/2020/015) UK
8/6/2020 Drug alert: Epistatus (Midazolam) 10mg/mL Oromucosal Solution (multi Dose Bottle) England
3/6/2020 Update – Early Access to Medicines Scheme for remdesivir in the treatment of COVID-19. Implementation of the scheme and management of supply UK
29/5/2020 MSN fluoxetine 40mg capsules England
29/5/2020 MSN: Caffeine Citrate 10mg in 1ml oral solution  England
29/5/2020 SDA: Zyban prolonged release tablets 150mg England
29/5/2020 SDA: Danazol capsules 100mg and 200mg England
28/5/2020 Medicines Defect information: Sodium benzoate sterile solution for injection 2g/10ml England
27/5/2020 Company led recall – Duavive modified release tablets England
26/5/2020 Early Access to Medicines Scheme for remdesivir in the treatment of COVID-19 UK
25/5/2020 SDA: Diamorphine hydrochloride 5mg and 10mg injection  England
22/5/2020 SDA Update- Neuromuscular blocking agents: atracurium, cisatracurium and rocuronium England
18/5/2020 COVID-19 General Case Definition Change UK
18/5/2020 CAS alert: ending the prescribing and supply of antiviral medicines in primary care for the influenza season 2019/20 UK
18/5/2020 Medicines Recall – Emerade injection 500mcg England
13/5/2020 SDA: Salazopyrin suppositories  500mg England
10/5/2020 CAS alert: Tiger Eye Protector Product – removal from the supply chain in respect of COVID-19 use England
7/5/2020 SDA: Phosphate polyfusor 500ml England
5/5/2020 CAS alert: COVID-19 Yellow Card reporting site launched by MHRA UK
6/5/2020 CAS alert: Recruiting patients for clinical trials for COVID-19 therapeutics England
1/5/2020 CAS alert: Message from the UK CMOs and Medical Directors of Public Health England and NHS England England

Monthly summary of letters and drug alerts that are sent to healthcare professionals and posted on the GOV.UK website

July 2020

June 2020

May 2020

April 2020

March 2020

February 2020

NPA Patient safety

The dedicated NPA webpage for all resources, updates and reports related to patient safety

MHRA alerts and recalls for drugs and medical devices

MHRA webpage for all published alerts and recalls for drugs and medical devices

MHRA CAS alerts

The MHRA Central Alerting System