The table below shows drug alerts, medicines recalls and company-led drug alerts issued in England, Northern Ireland, Scotland and Wales. The information in this table will be updated on an ongoing basis. Monthly summary of letters and drug alerts that are sent to healthcare professionals and posted on the GOV.UK website

 

Date published

Alert

Countries

17/05/2022 Class 2 Medicines Recall: Mefenamic acid  film coated tablets 500mg, Quadrant Pharmaceuticals Ltd, EL (22)A/23 UK
09/05/2022 Class 4 Medicines Defect Information: Zovirax I.V. 500 mg, GlaxoSmithKline UK Ltd, EL (22)A/22 UK
05/05/2022 Class 2 Medicines Recall: Accupro film-coated tablets 5mg, 10mg, 20mg, 40mg, Pfizer Limited, EL(22)A/21 UK
28/07/2022 Class 2 Medicines Recall: Sodium bicarbonate solution for infusion 1.26%, Fresenius Kabi Limited, EL(22)A/20 UK
27/04/2022 Class 2 Medicines Recall: Paroxetine  film coated tablets 40mg, Crescent Pharma Limited, EL(22)A/19 UK
21/04/2022 Class 4 Medicines Defect Information: Depo-Medrone with Lidocaine 40 mg/mL (1 mL and 2 mL vials – single vial preparations), Pfizer Limited, EL (22)A/18 UK
11/04/2022 Class 2 Medicines Recall: Olopatadine USV 1mg/ml Eye Drops, Solution, USV UK Limited, EL(22)A/17 UK
05/04/2022 NPSA: Inadvertent oral administration of potassium permanganate England
28/03/2022 Class 2 Medicines Recall: Accuretic film-coated tablets 10/12.5 mg, Pfizer Limited, EL (22)A/16 UK
17/03/2022 Class 4 Medicines Defect Information: Benzylpenicillin benzathine powder and solvent for suspension for injection, 1.2 Million I.U. and 2.4 Million I.U., EL (22)A/15 UK
15/03/2022 Class 4 Medicines Defect Information: Beclometasone dipropionate Nasal Spray 50 micrograms/dose (Various Liveries), Ayrton Saunders Limited, EL (22)A/14 UK
14/03/2022 Class 4 Medicines Defect Information: Latuda film-coated tablets, CNX Therapeutics Ltd, EL (22)A/13 UK
10/03/2022 Class 4 Medicines Defect Information: Decongestant Tablets and Decongestant with Pain Relief Tablets, Boots Company Plc, EL (22)A/12 UK
07/03/2022 Class 2 Medicines Recall: Diazepam RecTubes 2.5mg Rectal Solution, Wockhardt UK Ltd, EL (22)A/11 UK
04/03/2022 National Patient Safety Alert (UKHSA): Potential contamination of Alimentum and Elecare infant formula food products England
02/03/2022 Class 3 Medicines Recall: Isotard XL tablets 60mg, Kyowa Kirin Services Ltd., EL (22)A/10 UK
28/02/2022 UPDATE: Class 4 Medicines Defect Information: Naprosyn Tablets (all strengths), Naprosyn EC 250mg gastro-resistant tablets, Naprosyn EC 500mg gastro-resistant tablets, Atnahs Pharma UK Limited, EL (22)A/09 UK
23/02/2022 Class 4 Medicines Defect Information: Naprosyn tablets (all strengths), Naprosyn EC 500mg gastro-resistant tablets, Atnahs Pharma UK Limited, EL (22)A/09 UK
17/02/2022 Class 2 Medicines Recall: Fluorouracil Injection, 50 mg/ml, solution for injection (2500mg/50ml vial), Medac GmbH (t/a Medac Pharma LLP), EL (22)A 08 UK
17/02/2022 Class 2 Medicines Recall: Efudix cream 5% w/w, Uni Health Distribution, EL (22)A 07 UK
15/02/2022 Class 2 Medicines Recall: Water for Injections BP, 100ml vial, Hameln Pharma ltd, EL (22)A 06 UK
14/02/2022 Company led medicines recall: Bucain Hyperbar Solution for Injection 5mg/ml (unlicensed medicine), CLMR (22)A/01 UK
03/02/2022 Class 4 Medicines Defect Information: Atnahs Pharma UK Limited, Naprosyn Tablets (all strengths), Naprosyn EC 250mg Gastro-Resistant Tablets, EL (22)A/05 UK
01/02/2022 Class 4 Medicines Defect Information: Flamingo Pharma UK Ltd, Ibuprofen 400mg Tablets, EL (22)A/04 UK
31/01/2022 Class 4 Medicines Defect Information: Antibiotice SA, Piperacillin / Tazobactam 4g/0.5 g, powder for solution for infusion, EL (22)A/03 UK
25/01/2022 Class 4 Medicines Defect Information:  Fresenius Kabi Limited, Kabiven Emulsion for Infusion, EL (22)A/02 UK
19/01/2022 Class 2 Medicines Recall: SANTEN Oy (trading as Santen UK Limited) IKERVIS eye drops, emulsion, 1 mg/mL, EL (22)A/01 UK
30/12/2021 Company led medicines recall: Dermaved Sensitive Cream (unlicensed medicine), CLMR (21)A/09 UK
21/12/2021 Class 4 Medicines defect information: Benylin Chesty Coughs Original (P) and Benylin Chesty Coughs Non-Drowsy (GSL), EL(21)A/39 UK
21/12/2021 Supply disruption alert: Advanz epoprostenol 0.5mg and 1.5mg powder and solvent (pH10.5) solution for infusion vials UK
20/12/2021 Class 2 Medicines Recall: Heparin sodium 1,000 I.U./ml solution for injection or concentrate for solution for infusion, Wockhardt UK Ltd, EL (21)A/38 UK
16/12/2021 CMO Messaging: Neutralising monoclonal antibodies in the treatment of COVID-19 in hospitalised patients UK
16/12/2021 CMO Messaging: Neutralising monoclonal antibodies (nMABs) or antivirals for non-hospitalised patients with COVID-19 UK
16/12/2021 Class 4 Medicines Defect Information: SmofKabiven Central emulsion for Infusion, Fresenius Kabi Ltd, EL (21)A/37 UK
14/12/2021 CMO Messaging: Withdrawal of the Recommendation for Consideration of Inhaled Budesonide as a Treatment Option for COVID-19 UK
13/12/2021 Class 2 Medicines Recall: Lucentis solution for injection pre-filled syringe 10 mg/ml, 5ml, Novartis Pharmaceuticals UK, EL (21)A/36 UK
08/12/2021 Class 2 Medicines Recall: Mydrilate eye drops 0.5% 5ml, Intrapharm Laboratories Ltd, EL (21)A/35 UK
30/11/2021 Class 2 Medicines Recall: Various Marketing Authorisation Holders and parallel distributor companies, Irbesartan-containing products, EL(21)A/34 UK
29/11/2021 Class 4 Medicines Defect Information: Mometasone Furoate Nasal Spray, Suspension, 50 Microgram / Dose, PilsCo Ltd, EL (21)A/33 UK
29/11/2021 Class 4 Medicines Defect Information: Diuril Oral Solution (unlicensed medicine), Mawdsley-Brooks & Company Limited, EL (21)A/32 UK
28/11/2021 CMO messaging: Update on COVID-19 Variant B.1.1.529 UK
26/11/2021 CAS Supply disruption alert:  Hypovase (prazosin) 500 microgram tablets UK
22/11/2021 Class 3 Medicines Recall: Methadone 5mg Tablets / Physeptone 5mg Tablets, Martindale Pharma, an Ethypharm Group Company, EL (21)A/31 UK
18/11/2021 Class 2 Medicines Recall: IKERVIS eye drops, emulsion, 1 mg/mL and VERKAZIA eye drops, emulsion, 1 mg/mL, SANTEN Oy (trading as Santen UK Limited) and parallel distributor, EL (21)A/30 UK
17/11/2021 Company led medicines recall: Dotarem solution for injection (10ml Vial) – PL 12308/0016 UK
15/11/2021 Class 4 Medicines Defect Information: Slenyto prolonged-release tablets 1 mg and 5mg– distributed by Flynn Pharma Ltd, EL (21)A/29 UK
11/11/2021 Class 2 Medicines Recall: Cold & Flu Relief Capsules (GSL) – Various Liveries, Wrafton Laboratories Limited (trading as Perrigo), EL (21)A/28 UK
11/11/2021 National Patient Safety Alert: The safe use of ultrasound gel to reduce infection risk UK
02/11/2021 Class 4 Medicines Defect Information: SyreniRing 0.120 mg/0.015 mg per 24 hours, vaginal delivery system, Crescent Pharma Ltd, EL (20)A/36 UK
28/10/2021 Supply Disruption Alert: Champix (varenicline) 0.5mg and 1mg tablets England
26/10/2021 Class 3 Medicines Recall: Bimatoprost Aspire 0.3mg/ml eye drops, solution in single-dose container, Aspire Pharma Limited, EL (21)A/26 UK
14/10/2021 Class 2 Medicines Recall:  Champix (all strengths) film-coated tablets, Pfizer Ltd, EL (21)A/25 UK
12/10/2021 Class 2 Medicines Recall: Tesco Flu-Max All In One Chesty Cough & Cold Powder for Oral Solution (Wrafton Laboratoires Limited trading as Perrigo) EL (21)A/24 UK
11/10/2021 Supply disruption alert: Diazepam RecTubes® 2.5mg Rectal Solution (Wockhardt UK Ltd), SDA/2021/013 UK
27/09/2021 Class 2 Medicines Recall: Levothyroxine tablets 50mcg (Accord UK Ltd, trading as North Star), EL (21)A/23 UK
15/09/2021 Class 2 Medicines Recall: IKERVIS eye drops, emulsion, 1 mg/mL, SANTEN Oy (trading as Santen UK Limited), EL (21)A/22 UK
09/09/2021 Class 4 Medicines Defect Information: Rosuvastatin film-coated tablets, 5mg, 10mg, 20mg and 40mg, Accord Healthcare (EL (21)A/21) UK
25/08/2021 Class 2 Medicines Recall: Metformin Hydrochloride oral solution 500mg/5ml , Rosemont Pharmaceuticals Ltd, PL 00427/0139
UK
25/08/2021 National Patient Safety Alert: Infection risk when using FFP3 respirators with valves or Powered Air Purifying Respirators (PAPRs) during surgical and invasive procedures England
25/08/2021 National Patient Safety Alert: Elimination of bottles of liquefied phenol 80% England
18/08/2021 National Patient Safety Alert: Potent synthetic opioids implicated in increase in drug overdoses England
09/08/2021 Class 2 Medicines Recall: Irbesartan-containing products, various Marketing Authorisation Holders and parallel distributor companies, EL (21)A/19 UK
06/08/2021 Medicine Supply Alert Notice: Dalacin® (clindamycin) 2% vaginal cream Scotland
06/08/2021 Medicine Supply Alert Notice: Kolanticon gel® (2.5mg dicycloverine hydrochloride, 200mg aluminium hydroxide, 100mg light magnesium oxide, 20mg simethicone per 5ml) Scotland
06/08/2021 Medicine Supply Alert Notice: Tuberculosis (TB) oral agents Scotland
02/08/2021 Supply disruption alert: Glipizide tablets (Minodiab) 5mg  UK
29/07/2021 Supply disruption alert: Tinzaparin sodium (10,000 IU/ml) 3,500 units in 0.35ml and 4,500 units in 0.45ml pre-filled syringes UK
19/07/2021 Class 4 Medicines Defect Notification: Amoxicillin 500 mg/ 5 ml Powder for oral suspension, (PL 25298/0248), EL (21)A/18 UK
12/07/2021 Class 4 Medicines Defect Notification: Sevredol tablets10 mg and 20mg, Napp Pharmaceuticals Ltd,(PL 16950/0063, PL 16950/0064), EL (21)A/17 UK
06/07/2021 Class 4 Medicines Defect Notification: Tetralysal hard capsules 300mg, Galderma UK (PL 10590/0019), EL (21)A/16 UK
01/07/2021 Class 2 Medicines Recall: Xomolix solution for injection 2.5mg/ml, Kyowa Kirin Limited UK
01/07/2021 Company led medicines recall: Morphine Syringe 50mg/50ml (unlicensed medicine) and Magnesium Sulphate 8mmol/20ml infusion (unlicensed medicine) UK
25/06/2021 Supply disruption alert: Dexamethasone 0.1% (Maxidex) 5ml eye drops UK
24/06/2021 Supply disruption alert: Champix (varenicline) tablets 0.5mg and 1mg UK
23/06/2021 National Patient Safety Alert: Philips ventilator, CPAP and BiPAP devices: Potential for patient harm due to inhalation of particles and volatile organic compounds UK
17/06/2021 Class 2 Medicines Recall: Bristol Laboratories Limited, Brown & Burk UK Ltd, Teva UK Ltd, Irbesartan-containing and Losartan-containing products, EL (21)A/14 UK
16/06/2021 Class 1 Medicines Recall Notification: Co-codamol 30/500 Effervescent Tablets, Batch 1K10121, Zentiva Pharma UK Ltd, NatPSA/2021/004/MHRA UK
16/06/2021 CAS alert: NatPSA: Eliminating the risk of inadvertent connection to medical air via a flowmeter England
14/06/2021 CAS alert: Updated Publication of Remdesivir guidance for patients hospitalised with Covid-19 (adults and children aged 12 years and older) England
09/06/2021 Company led medicines recall: Noidecs T20/C4 (THC 20%; CBD <4%) Indica Cannabis Flower (unlicensed medicine) and Noidecs T20/C4 (THC 20%; CBD <4%) Sativa Cannabis Flower (unlicensed medicine) UK
09/06/2021 CAS alert: Personal protective equipment and heat: risk of heat stress England
20/05/2021 Class 3 Medicines Recall: Carbimazole tablets 10mg and 15mg, Advanz Pharma, EL (21)A/13 UK
19/05/2021 National Patient Safety Alert: Urgent assessment/treatment following ingestion of ‘super strong’ magnets England
17/05/2021 Class 2 Medicines Recall: Bricanyl Injection, 0.5 mg/ml solution for injection or infusion (PL 17901/0112), AstraZeneca UK Limited, EL (21)A/12 UK
04/05/2021 Class 4 Medicines Notification: Syonell gastro-resistant tablets  250mg and 500mg, Lupin Healthcare Ltd, EL (21)A/11 UK
22/04/2021 Medicine Supply Alert Notice: Pioglitazone 15mg/metformin 850mg (Competact®) tablets Scotland
22/04/2021 Class 2 Medicines Recall: Trimethoprim tablets 200mg, Ennogen Pharma Limited, PL 40147/0083 UK
15/04/2021 Medicine Supply Alert Notice: Chloral Hydrate 143.3mg in 5ml oral solution Scotland
15/04/2021 Medicine Supply Alert Notice: Diamorphine hydrochloride powder for reconstitution and injection 5mg and 10mg ampoules  Scotland
15/04/2021 Medicine Supply Alert Notice: Voriconazole (VFEND®) 40mg/ml powder for oral suspension Scotland
15/04/2021 Medicine Supply Alert Notice: Rifinah® 300mg/150mg (rifampicin 300mg/isoniazid 150mg) tablets Scotland
15/04/2021 COVID-19 – MHRA ADVICE – VACCINE ASTRAZENECA AND THROMBOEMBOLIC
EVENTS WITH CONCURRENT LOW PLATELETS – REVISIONS TO PRODUCT
INFORMATION
Scotland
12/04/2021 CMO messaging: COVID-19 Therapeutic Alert – Inhaled Budesonide for Adults (50 Years and Over) with COVID-19 UK
31/03/2021 Medicine Supply Alert Notice: H2-antagonists (cimetidine, famotidine and nizatidine) Scotland
31/03/2021 Medicine Supply Alert Notice: Oral Contraceptive tablets (various brands) Scotland
23/03/2021 Medicine Supply Alert Notice: Irbesartan/hydrochlorothiazide 150mg/12.5mg tablets Scotland
23/03/2021 Medicine Supply Alert Notice: Enalapril 5mg tablets Scotland
18/03/2021 Class 4 Medicines Defect Information: Caffeine Citrate Solution for Injection 10mg/ml, Macarthys Laboratories Limited T/A Martindale Pharma  UK
16/03/2021 Medicine Supply Alert Notice: Repaglinide tablets 1mg and 2mg Scotland
15/03/2021 Class 3 Medicines Recall: Itraconazole Oral Solution 10mg/ml, Thame Laboratories, EL (21)A/08 UK
12/03/2021 CMO messaging: Updated information for clinicians/health care professionals on Covid-19 PCR testing England
09/03/2021 Class 4 Medicines Defect Information: Diazepam Oral Solution Sugar Free 2mg/5ml (EL (21)A/07) (PL 0142/0103), Accord-UK Ltd UK
08/03/2021 Medicine Supply Alert Notice: Colestid® (colestipol) orange and plain 5g granules sachets Scotland
08/03/2021 Medicine Supply Alert Notice: Desmopressin (Octim®) 150 micrograms per actuation nasal spray (Ferring Pharmaceuticals) – update to MSAN(2020)95 Scotland
08/03/2021 Medicine Supply Alert Notice: Docusate sodium 100mg capsules – update MSAN(2020)119 Scotland
08/03/2021 Medicine Supply Alert Notice: Fluoxetine 10mg tablets – update to MSAN(2020)16 Scotland
08/03/2021 Medicine Supply Alert Notice: Sancuso® (granisetron) 3.1mg/24 hours transdermal patches Scotland
05/03/2021 Medicine Supply Alert Notice:  Morphine sulphate (MST CONTINUS®) 20mg, 30mg, 60mg, 100mg and 200mg prolonged release granules for oral suspension Scotland
04/03/2021 CAS alert: Changes to MHRA Drug Alert titles and classifications UK
04/03/2021 CAS alert: Repaglinide tablets 1mg and 2mg – Supply Disruption England
02/03/2021 Medicine Supply Alert Notice: Acetazolamide SR capsules 250mg  Scotland
02/03/2021 Medicine Supply Alert Notice: Fluoxetine capsules 40mg  Scotland
01/03/2021 Serious Shortage Protocol: Levothyroxine tablets 12.5 microgram Scotland
01/03/2021 Class 3 Medicines Recall: Easyhaler Salbutamol Sulfate 100 micrograms per actuation/200 micrograms per actuation inhalation powder, EL (21)A/06 UK
26/02/2021 CAS alert – Discontinuation of Morphine sulphate (MST CONTINUS) 20mg, 30mg, 60mg, 100mg and 200mg prolonged release granules for oral suspension England
24/02/21 CAS alert – Class 1 Recall: Fang Tian FT-045A FFP3 masks RECALL – Immediate Action Required UK
23/02/2021 Medicine Supply Alert Notice: Phyllocontin® (Aminophylline) modified release tablets 225mg and 350mg  Scotland
18/02/2021 CAS alert – Class 1: Fang Tian FT-045A FFP3 masks – Immediate Action Required UK
17/02/2021 CMO Messaging: Interleukin-6 Inhibitors (Tocilizumab Or Sarilumab) For Hospitalised Patients With Covid-19 Pneumonia (Adults) UK
17/02/2021 Class 3 Medicines Recall: SyriMed, Clonidine hydrochloride 50micrograms/5ml Oral Solution, EL (21)A/05 UK
16/02/2021 Class 2 Medicines Recall: Eaststone Limited, MidaBuc – Midazolam (as HCL) 10mg/mL Oromucosal Solution, EL (21)A/04 UK
12/02/2021 CAS alert: Phyllocontin (Aminophylline) 225mg and 350mg modified release tablets (update on SDA/2021/003 issued on 9 February 2021) – Supply disruption England
12/02/2021 CMO messaging: Colchicine in the Management of COVID-19 (SARS-CoV 2) Positive Patients – Trial Use Only UK
11/02/2021 Class 4 Medicines Defect Information: AmBisome Liposomal 50 mg Powder for dispersion for infusion, (PL 16807/0001), EL (21)A/03 UK
09/02/2021 CAS alert: Phyllocontin (Aminophylline) 225mg and 350mg modified release tablets – Supply disruption England
08/02/2021 Class 2 Medicines Recall: Grünenthal Ltd, Palexia 20 mg/ml Oral Solution (PL 21727/0054) UK
03/02/2021 CAS alert: Propofol emulsion for infusion and injection (all strengths) – Supply disruption England
03/02/2021 Class 3 Medicines Recall: Intrapharm Laboratories Ltd, Kolanticon Gel 500ml, EL (21)A/01 UK
02/02/2021 CAS alert: Changes to MHRA Drug Alerts UK
01/02/2021 CMO Messaging: Interleukin-6 inhibitors (tocilizumab and sarilumab) for critically ill patients with COVID-19 pneumonia (adults) UK
28/01/2021 CMO Messaging: COVID-19 Therapeutic Alert – Antimicrobials (azithromycin and doxycycline) Not Beneficial in the Management of COVID-19 (SARS-CoV-2) Positive Patients UK
18/1/2021 Company led medicines recall: Instanyl 100mcg nasal spray solution ( EU/1/09/531/015) UK
14/1/2021 Supply disruption alert: Methylprednisolone powder for solution for injection (all strengths) – Supply disruption
England
12/1/2021 CMO Messaging: Supporting doctors throughout the COVID-19 pandemic
England
8/1/2021 COVID-19 Therapeutic Alert: Interleukin-6 inhibitors (tocilizumab or sarilumab) for patients admitted to ICU with COVID-19 pneumonia (adults) UK
4/1/2021 CMO Messaging: Letter from the UK Chief Medical Officers regarding the UK COVID-19 vaccination programmes
UK
4/1/2021 Supply Disruption Alert – Update: Lithium carbonate (Priadel®) 200mg and 400mg tablets  England
29/12/2020 Class 2 Medicines Recall: Sodiofolin 50mg/ml Solution for Injection 100mg/2ml, PL 11587/0005, medac GmbH (t/a medac Pharma LLP) UK
29/12/2020 Medicine supply alert notice: Phytomenadione (Konakion MM Paediatric) 2mg/0.2ml ampoules (Cheplapharm) Scotland
29/12/2020 Medicine supply alert notice: Zemtard® (diltiazem) 240mg XL capsules Scotland
29/12/2020 Medicine supply alert notice: Rifadin® (rifampicin) 100mg/5ml oral suspension Scotland
29/12/2020 Medicine supply alert notice: Dulcolax® (bisacodyl) 5mg and 10mg suppositories  Scotland
29/12/2020 Medicine supply alert notice: Docusate sodium 100mg capsules Scotland
23/12/2020 CMO Messaging: Indemnity arrangements for the Covid-19 vaccination programme England
15/12/2020 Class 4  Medicines Defect Information: Co-Careldopa 25mg/100mg tablets PL 20242/0028, Fairmed Healthcare GmbH  UK
16/12/2020 Class 2 Drug Alert: Zerbaxa 1g/0.5g Powder for Concentrate for Solution for
Infusion
Scotland
14/12/2020 Class 4  Medicines Defect Information: Perindopril Erbumine  tablets 2mg, 4mg, 8mg – Generics [UK] Limited t/a Mylan UK
08/12/2020 Medicine Supply Notification: Buprenorphine (Butec) 15microgram/hour patches (7-day) UK
03/12/2020 Class 3 Medicines Recall: Simvador 10mg Tablets, Simvador 20mg Tablets, Simvador 40mg Tablets – Lupin Healthcare (UK) Limited  UK
30/11/2020 Medicine Supply Notification: Dulcolax (bisacodyl) 5mg and 10mg suppositories UK
30/11/2020 Medicine Supply Notification: Nalcrom (sodium cromoglicate) 100mg capsules UK
30/11/2020 Medicine Supply Notification: Sterculia (Normacol) 62% w/w granules, Sterculia & Frangula Bark (Normacol Plus) 62%/8% w/w granules UK
30/11/2020 Medicine Supply Notification: Ferrous Fumarate 322mg/Folic Acid 350mcg (Pregaday) tablets (Recipharm) UK
30/11/2020 Medicine Supply Notification: Oral Contraceptive tablets (various brands)  UK
26/11/2020 Class 2 Medicines Recall: Largactil 50mg/2ml Solution for Injection PL 04425/0582, Aventis Pharma Limited (t/a Sanofi) UK
26/11/2020 Class 2 Medicines Recall: Betahistine dihydrochloride 8mg Tablets, Betahistine dihydrochloride 16mg Tablets, Kent Pharmaceuticals Ltd UK
25/11/2020 Class 2 Medicines Recall: Abstral 200 microgram sublingual tablets PL 16508/0031, Kyowa Kirin Limited UK
17/11/2020  Medicine supply alert notice: Dulcolax® (bisacodyl) 5mg and 10mg suppositories  Scotland
17/11/2020  Medicine supply alert notice: Trifluoperazine 1mg/5ml syrup (Advanz Pharma)  Scotland
12/11/2020 Class 2 Medicines Recall: Ancotil 2.5 g/250 ml Solution for Infusion, PL 46302/0116, Mylan UK Healthcare Ltd UK
11/11/2020 Class 2 Medicines Recall: medac GmbH (t/a medac Pharma LLP)
Sodiofolin 50mg/ml Solution for Injection 100mg/2ml PL 11587/0005 
UK
09/11/2020 Medicine supply alert notice: Haloperidol 5mg/5ml oral solution sugar free (Thame Laboratories)  Scotland
09/11/2020 Medicine supply alert notice: Nalcrom® (sodium cromoglicate) 100mg capsules  Scotland
09/11/2020 Medicine supply alert notice: H2-antagonists (cimetidine, famotidine and nizatidine)  Scotland
09/11/2020 Medicine supply alert notice: Zonisamide capsules various strengths (Glenmark and Teva)  Scotland
09/11/2020 Medicine supply alert notice: Prednisolone 5mg Suppositories (RPH Pharmaceuticals)  Scotland
09/11/2020 Class 4 drug alert –  Kolanticon gel 200ml (PL 17509/0084), Intrapharm Laboratories Limited UK
07/11/2020 Immediate actions in response to mink-variant SARS-CoV-2 virus in Denmark England
29/10/2020 Class 3 Medicines Recall: Theramex Ireland Ltd T/A Theramex HQ UK Ltd, AlfaD 0.25 microgram capsules UK
23/10/2020 Medicine supply alert notice: Ferrous Fumarate 322mg/Folic Acid 350microgram (Pregaday®) tablets (Recipharm) Scotland
23/10/2020 Medicine supply alert notice: Fluoxetine 30mg capsules (Advanz) Scotland
23/10/2020 Medicine supply alert notice: Salazopyrin En-Tabs® (sulfasalazine) 500mg tablets Scotland
21/10/2020 Medicine supply alert notice: Dulcolax® (bisacodyl) 5mg suppositories Scotland
21/10/2020 Medicine supply alert notice: DDAVP® (Desmopressin) 0.01% w/v (100 micrograms/ml) intranasal solution Scotland
15/10/2020 Medicine supply alert notice: Lithium carbonate (Priadel®) 200mg and 400mg modified release tablets Scotland
14/10/2020 Class 3 Medicines Recall: Metoprolol 50 mg Tablets Accord Healthcare Ltd. UK
14/10/2020 Class 2 Medicines Recall: Epilim 500mg Gastro-Resistant Tablets UK
9/10/2020 Medicine supply alert notice: Sterculia (Normacol®) 62% w/w granules; Sterculia & Frangula Bark (Normacol Plus®) 62%/ 8% w/w granules Scotland
9/10/2020 Medicine supply alert notice: Oral Contraceptive tablets (various brands) Scotland
9/10/2020 Medicine supply alert notice: H2-antagonists (cimetidine, famotidine and nizatidine) Scotland
9/10/2020 Medicine supply alert notice: Lorazepam (Ativan®) 4mg/ml Solution for injection (Pfizer) Scotland
9/10/2020 Medicine supply alert notice: Desmopressin (Octim®) 150 micrograms per actuation nasal spray (Ferring Pharmaceuticals) Scotland
6/10/2020 Class 2 Medicines Recall: Boots Dermacare 1% w/w Hydrocortisone Ointment (P)
UK
30/9/2020 MHRA supply disruption alert: Remdesivir
England
29/9/2020 Medicine supply alert notice: Tuberculosis (TB) oral agents Scotland
29/9/2020 Medicine supply alert notice: Enalapril 20mg tablets (various suppliers) Scotland
29/9/2020 Medicine supply alert notice: Metronidazole (Acea®) 0.75% gel (Ferndale Pharmaceuticals) Scotland
29/9/2020 Medicine supply alert notice: Fluticasone propionate (Flixotide®) 0.5mg/2ml and 2mg/2ml Nebules Scotland
29/9/2020 Medicine supply alert notice: Zonisamide 50mg and 100mg capsules(Teva)
Scotland
29/9/2020 Class 3 Medicines Recall: AlfaD 0.25mcg capsules and AlfaD 1mcg capsules
UK
29/9/2020 Medicine supply alert notice: Normacol and Normacol Plus England and Scotland
18/9/2020 MHRA alert – Important changes to MHRA alerts and amendments to CAS website UK
16/9/2020 Class 2 FMD Medicines Recall: multiple parallel distributed medicines
UK
10/9/2020 CMO messaging: withdrawal of PPE guidance published 17 April 2020 England
10/9/2020 Class 4 Medicines Defect information: Zopiclone tablets UK
7/9/2020 Class 3 Medicines Recall: Amlodipine 10mg Tablets UK
3/9/2020 Medicine supply notice: Lithium carbonate (Priadel®) 200mg and 400mg modified release tablets  Scotland
1/9/2020 Class 4 FMD Medicines Information: Kingsley Specials Ltd UK
1/9/2020 Class 2 Medicines Recall: Oxylan prolonged-release tablets 40mg UK
27/8/2020 Medicine supply alert notice: Esomeprazole 40mg iv powder for solution Scotland
26/8/2020 Medicine supply alert notice: H2-antagonists (cimetidine, famotidine and nizatidine) Scotland
26/8/2020 Medicine supply alert notice: Oral Contraceptive tablets (various brands) Scotland
26/8/2020 Medicine supply alert notice: Diazepam (Diazemuls®) emulsion for injection 10mg/2ml Scotland
26/8/2020 Medicine supply alert notice: Prednisolone suppositories 5mg Scotland
26/8/2020 Medicine supply alert notice: Nabumetone tablets 500mg Scotland
26/8/2020 Medicine supply alert notice: Lodoxamide eye drops 01% Scotland
25/8/2020 Drug alert: Update: Amoxicillin Sodium Powder for Solution for Injection 1g, 250mg and 500mg (Wockhardt UK Ltd) UK
24/8/2020 Class 2 drug alert Action within 48 hours: Fasturtec powder and solvent for concentrate for solution for infusion 7.5mg/5ml (Sanofi) England
21/8/2020 Supply disruption alert: Priadel® modified-release tablets 200mg and 400mg England
18/8/2020 CMO Messaging: COVID-19 Research and treatment trials England
14/8/2020 PPE dedicated supply channel important customer alert: Flosteril FLO-MED-8130 non-sterile gowns England
13/8/2020 Drug Alert: SmofKabiven extra Nitrogen Electrolyte Free UK
13/8/2020 NPSA alert: Steroid Emergency Card to support early recognition and treatment of adrenal crisis in adults England
11/8/2020 Medicine supply alert notice: Pethidine 50mg tablets Scotland
11/8/2020 Medicine supply alert notice: Sulfasalazine 250mg-5ml oral suspension (Rosemont) Scotland
10/8/2020 Drug alert: Phosphates Solution for Infusion 500ml (Huddersfield Pharmacy Specials MS 19055) UK
6/8/2020 NPSA alert: Risk of death from unintended administration of sodium nitrite England
5/8/2020 Medicine supply alert notice: Tuberculosis (TB) oral agents Scotland
5/8/2020 Medicine supply alert notice: Senna with ispaghula husk (Manevac®) granules (Mylan) Scotland
5/8/2020 Medicine supply alert notice: Nabumetone 500mg Tablets Scotland
5/8/2020 Medicine supply alert notice: H2-antagonists (cimetidine, famotidine and nizatidine) Scotland
4/8/2020 Drug alert: Clexane 4,000 IU (40mg) /0.4ml Syringes (Pharmaram Ltd) Scotland
4/8/2020 Drug alert: Clexane 4,000 IU (40mg)/0.4ml Syringes (Pharmaram Ltd) England, Northern Ireland and Wales
3/8/2020

Medicines defect information: SyreniRing vaginal delivery system 0.120mg/0.015mg per 24 hours (Crescent Pharma Ltd)

UK
3/8/2020

Drug recall: Digoxin tablets 250mcg (Accord-UK Ltd)

UK
29/7/2020

Drug recall: Abstral sublingual tablets 200mcg (Kyowa Kirin Limited)

UK
24/7/2020

Evidence of harm from illicit or fake benzodiazepines

England
23/7/020

Drug Recall:  Irinotecan hydrochloride concentrate for solution for infusion 20mg/ml (5ml vial)

England, Northern Ireland and Scotland
23/7/2020 Drug Alert: information Ecalta 100mg powder for concentrate for solution for infusion England, Northern Ireland and Scotland
21/7/2020 DHSC alert: cannabis oil has been found disguised as confectionary England
20/7/2020

Drug alert: Trimogal tablets 100mg (Ennogen Pharma)

England and Scotland
20/7/2020

Medical device alert: Cardinal Health type IIR facemasks alert

England
20/7/2020

Drug alert: Ibuprofen 200mg and 400mg tablets packaged in various liveries (Aspar Pharmaceuticals Limited)

Scotland
20/7/2020

Drug alert: Ibuprofen 200mg and 400mg tablets packaged in various liveries (Aspar Pharmaceuticals Limited)

Northern Ireland 
20/7/2020

Drug alert: Ibuprofen 200mg and 400mg tablets packaged in various liveries (Aspar Pharmaceuticals Limited)

England and Wales
15/7/2020

Drug Alert: Nitrofurantoin tablets 50mg, Dr Reddy’s Laboratories (UK) Ltd (15/07/2020)

England, Northern Ireland and Wales
15/7/2020

Drug Alert: Desmopressin nasal spray (all strengths) Ferring Pharmaceuticals Limited

England, Scotland and Wales
15/7/2020

Drug alert: Desmospray® 0.1 mg/ml Nasal Spray 

Northern Ireland
8/7/2020

MSN: Pregaday® (ferrous fumarate 322mg/folic acid 350mcg) tablets (08/07/20)

England, Northern Ireland and Scotland
8/7/2020

MSN: Intal® (sodium cromoglicate) CFC-free inhaler 5mg/dose (08/07/20)

England and Northern Ireland
1/7/2020 MSN: Mitomycin 2mg England
01/7/2020 Drug Recall: Mepacrine hydrochloride tablets 100mg UK
30/6/2020 Drug Alert: Depo-Provera injection 150mg/ml England, Scotland, Northern Ireland
30/6/2020 Medicine supply alert: Fluticasone propionate (Flixotide®) 0.5mg/2ml and 2mg/2ml Nebules Scotland
30/6/2020 Medical drug alert: Philips HeartStart XL Defibrillator/Monitor England
29/6/2020

Drug safety alert: Reducing the risk of meningioma with cyproterone acetate

UK
29/6/2020

Drug safety alert: Direct-acting oral anticoagulants (DOACs) — increased bleeding risk

UK
29/6/2020 Medicine supply alert: Prednisolone 5mg Suppositories (RPH Pharmaceuticals) Scotland
29/6/2020 Medicine supply alert: Promazine 25mg and 50mg tablets Scotland
29/6/2020 Medicine supply alert: Phenytoin sodium NRIM 100mg capsules Scotland
26/6/2020

Customer alert: Cardinal Health Type IIR masks alert

UK
26/6/2020

MHRA approves recruitment of further participants into hydroxychloroquine clinical trial

UK
25/6/2020 MSN: Flixotide nebules England
25/06/20 SDA: Nardil® (Phenelzine sulphate) tablets 15mg (25/06/20) England, Northern Ireland, Wales
25/06/20 MSN: Mirtazapine orodispersible tablets 15mg and 45mg UK
25/6/2020 MSN: Alomide® (lodoxamide) eye drops 0.1% England, Northern Ireland, Scotland
25/6/2020 MSN: Imipramine tablets 25mg UK
25/6/2020 MSN: Vimpat® (lacosamide) tablets 50mg England
23/6/2020 CAS alert: risk of heat stress whilst wearing PPE in warn/hot weather England
19/6/2020 Medicine supply alert: H2-antagonists (cimetidine, famotidine and nizatidine) Scotland
18/6/2020 MSN TB oral agents Update 7 England
17/6/2020 Medical device alert: Philips HeartStart MRx Monitor/Defibrillators England
16/6/2020 MSN: levodopa +carbidopa+ entacapone tablets- various strengths and brands England
16/6/2020 CAS alert: Dexamethasone approved to treat hospitalised COVID-19 patients UK
12/6/2020 MSN: Ranitidine- all formulations (clinical update) England
12/6/2020 MSN: oxaliplatin Update England
10/6/2020 MSN: Prednisolone 5mg Suppositories England
9/6/2020 Second update – Early Access to Medicines Scheme for Remdesivir in the treatment of COVID-19. Implementation of the scheme and management of supply UK
8/6/2020 MSN: Solu-Medrone 1g England
8/6/2020 MHRA medical device alert (8/6/20) ISSUED: Results from laboratory-based tests for COVID-19 antibodies using capillary blood sample collection kits may not be reliable (MDA/2020/015) UK
8/6/2020 Drug alert: Epistatus (Midazolam) 10mg/mL Oromucosal Solution (multi Dose Bottle) England
3/6/2020 Update – Early Access to Medicines Scheme for remdesivir in the treatment of COVID-19. Implementation of the scheme and management of supply UK
29/5/2020 MSN fluoxetine 40mg capsules England
29/5/2020 MSN: Caffeine Citrate 10mg in 1ml oral solution  England
29/5/2020 SDA: Zyban prolonged release tablets 150mg England
29/5/2020 SDA: Danazol capsules 100mg and 200mg England
28/5/2020 Medicines Defect information: Sodium benzoate sterile solution for injection 2g/10ml England
27/5/2020 Company led recall – Duavive modified release tablets England
26/5/2020 Early Access to Medicines Scheme for remdesivir in the treatment of COVID-19 UK
25/5/2020 SDA: Diamorphine hydrochloride 5mg and 10mg injection  England
22/5/2020 SDA Update- Neuromuscular blocking agents: atracurium, cisatracurium and rocuronium England
18/5/2020 COVID-19 General Case Definition Change UK
18/5/2020 CAS alert: ending the prescribing and supply of antiviral medicines in primary care for the influenza season 2019/20 UK
18/5/2020 Medicines Recall – Emerade injection 500mcg England
13/5/2020 SDA: Salazopyrin suppositories  500mg England
10/5/2020 CAS alert: Tiger Eye Protector Product – removal from the supply chain in respect of COVID-19 use England
7/5/2020 SDA: Phosphate polyfusor 500ml England
5/5/2020 CAS alert: COVID-19 Yellow Card reporting site launched by MHRA UK
6/5/2020 CAS alert: Recruiting patients for clinical trials for COVID-19 therapeutics England
1/5/2020 CAS alert: Message from the UK CMOs and Medical Directors of Public Health England and NHS England England

July 2020

June 2020

May 2020

April 2020

March 2020

February 2020

NPA Patient safety

The dedicated NPA webpage for all resources, updates and reports related to patient safety

MHRA alerts and recalls for drugs and medical devices

MHRA webpage for all published alerts and recalls for drugs and medical devices

MHRA CAS alerts

The MHRA Central Alerting System